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This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.Systematic review on the management of irritable bowel syndrome in North America.

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Advantages of clonidine over methadone in the treatment of opioid withdrawal are as follows: One disadvantage to methadone detoxification with naltrexone an opioid antagonist as compared with clonidine, is that naltrexone, when it is prescribed for abstinence, can precipitate opioid withdrawal if given too soon after the last methadone dose.

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Patients who may be taking such medications need to be carefully observed and have their medications carefully monitored.Enoch MA, Problem drinking and alcoholism: diagnosis and treatment. Am Fam Physician.


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